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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MFF All Species: 8.07
Human Site: S7 Identified Species: 17.76
UniProt: Q9GZY8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZY8 NP_064579.3 342 38465 S7 _ M S K G T S S D T S L G R V
Chimpanzee Pan troglodytes XP_516131 372 41638 T37 R A G V L A G T L L W A Q G V
Rhesus Macaque Macaca mulatta XP_001110642 341 38439 S7 _ M I K R T S S D T P L G R V
Dog Lupus familis XP_850079 342 38482 S7 _ M S E R T S S D T P L G R V
Cat Felis silvestris
Mouse Mus musculus Q6PCP5 291 32913
Rat Rattus norvegicus Q4KM98 218 24952
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519323 251 27935
Chicken Gallus gallus XP_001233530 330 37495 P9 S G A A F P S P A A E M A E I
Frog Xenopus laevis Q6DD53 219 24655
Zebra Danio Brachydanio rerio Q503U3 275 31342
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198768 213 23716
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.5 97.6 95 N.A. 80.1 60.5 N.A. 63.1 81.5 42.4 45.3 N.A. N.A. N.A. N.A. 20.1
Protein Similarity: 100 90.3 98.2 97 N.A. 82.4 62.8 N.A. 67.5 88.8 50.2 61.4 N.A. N.A. N.A. N.A. 34.8
P-Site Identity: 100 6.6 78.5 78.5 N.A. 0 0 N.A. 0 6.6 0 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 13.3 78.5 85.7 N.A. 0 0 N.A. 0 26.6 0 0 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 0 10 0 0 10 10 0 10 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 28 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 10 0 0 10 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 0 10 0 10 0 0 0 0 0 28 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 10 10 0 28 0 0 0 % L
% Met: 0 28 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 10 0 0 19 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 10 0 0 0 19 0 0 0 0 0 0 0 0 28 0 % R
% Ser: 10 0 19 0 0 0 37 28 0 0 10 0 0 0 0 % S
% Thr: 0 0 0 0 0 28 0 10 0 28 0 0 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 28 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _